Entering the winter break, United have been given a huge boost in their bid for the top four in the Premier League.
Ralph Lonnick's side had an almost perfect weekend at the end of January, beating West Ham to reach the Champions League, with Tottenham Hotspur and Arsenal behind.
United now have a slim margin over their opponents, who are only one point away from the Hammers and two points between the Gunners and Spurs.
But with the two North London clubs playing, the battle for fourth place looks set to go straight, and the next six league games could prove crucial.
Burnley (Guest)
Usually, a trip to Tefmore can make the team a little nervous, especially if they go there and need a win.
But this season, Burnley are at the bottom of the table, and so far they have only won one game, and United hope that this time there will be no mistakes.
However, they certainly won't let Manchester United win easily, as can be seen from their draw with Arsenal, so it is still not easy to take it lightly.
Southampton (Main)
We are unlikely to see a repeat of last season's spectacular 9-0 win – although that may just be the southampton player's memory of Old Trafford.
They tend to be a tricky team that can have some impressive performances and results, but also have some bad performances.
While their recent draw with Manchester City suggests they are not a team to be taken lightly, at home, United are expected to pick up three points here.
Leeds (Guest)
Ahead of beating Newcastle, several important wins against Burnley and West Ham looked like they were finally on track.
They are missing Phillips and it looks like he will still be absent from United's game next month.
Playing against Leeds United has always been a good thing for United, although recent big wins suggest Thatersa's side may not be weak on the defensive end.
Watford (Main)
What United face in this game will largely depend on who will be in charge of Watford at that time.
After being beaten 3-0 by Norwich, they fell into the relegation zone and some believe the Italian coach is close to leaving.
But in any case, United should make the most of a team facing relegation to come to Old Trafford.
Manchester City (Guest)
Things get a little harder in March, with a Manchester derby waiting to kick off for the month.
Manchester City are by far the best team in the league and it takes some effort to get a result – because it's a derby game, it's even more important to prepare.
Tottenham Hotspur (Main)
In terms of contention for the top four, it was a huge game for United.
They have scored 3 points in Tottenham Hotspur this season, but this time they will be a very different beast under Antonio Conte.
If United can score huge three-pointers here, it could be a decisive blow to the competition in the top four.