Both safe and secure can mean "safe". But the emphasis of each word is different.
Safe means to be out of danger, free from harm, protected, and safe. Focus on the absence of danger and damage, in a state of peace.
Example Sentence 1: She returned safe and sound from a dangerous expedition.
Example Sentence 2: The plane crashed but the crew were safe.

Complementary learning: safely and safeety can also mean "safe." It's just that the parts of speech are different. The former is an adverb, while the latter is used as a noun
Example Sentence 1: He arrived safely and he arrived safely
Example Sentence 2: They ran to safety, away from the fire.
Second, secure means to be safe from danger. Focus on protection or care so that they are not harmed, free from danger, or safe by eliminating foreseeable dangers. Generally interchangeable with safe, but more significant, more emphasis on stability, free from worries, worries.
Example Sentence 1: I don't feel secure when i am alone in the house.
Example Sentence 2: The strong-room is as secure as we can make it.
Summary: Both safe and secure can mean "safe", safe focuses on the state of peace, and secure focuses on the mentality of feeling safe and secure.