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"20-in-1" is a key step in gaining valuable time

author:Xining Municipal Health Commission
"20-in-1" is a key step in gaining valuable time

Recently, the medical treatment team of the joint prevention and control mechanism of the State Council issued the "Technical Specifications for the Detection of Nucleic Acids of the New Coronavirus 20-in-1 Mixed Extraction". Steadily promoting the 20-in-1 mixed detection technology of nucleic acids of the new crown virus is a key step in winning valuable time for epidemic prevention and control, and it is also another example of the further improvement of the mainland's ability to cope with the new crown pneumonia epidemic.

Recently, large-scale nucleic acid screening of the new crown virus has been carried out in many parts of the country, such as Xi'an City in Shaanxi Province, Zhengzhou City in Henan Province, Tianjin City in Tianjin City, And Zhuhai City in Guangdong Province. Some cities have reported native cases of Aumiqueron that are more contagious than Delta. Among them, there are many cities with a population of more than 10 million, and it can be said that the task of conducting large-scale nucleic acid screening in a short period of time can be said to be extremely arduous. Compared with the current 5-in-1, 10-in-1 mixed collection detection technology, the emergence of 20-in-1 mixed collection detection technology can be described as a timely rain for large-scale population nucleic acid screening work, which can not only quickly double the efficiency, but also reduce costs, reduce workload, and most importantly, win time for outperforming the virus.

The implementation of the "four early" principles of early detection, early reporting, early isolation and early treatment is a powerful measure for the prevention and control of the new crown pneumonia epidemic. Under the guidance of this principle, the mainland's experience in epidemic prevention and control has been continuously upgraded. The iterative upgrading of nucleic acid detection technology has contributed wisdom and strength to further improve the ability and efficiency of nucleic acid detection and implement the "four early" principle. At this stage, the mainland adheres to the general principle of "dynamic zero clearance", adopts comprehensive prevention and control measures when local cases occur, and quickly extinguishes the epidemic. This is the "fast knife", which is the best choice to seize time, compete for speed, and control the epidemic to the minimum extent. The practice of epidemic prevention and control in the mainland has proved that if various measures can be basically deployed in place within 24 hours after the outbreak of the epidemic, the risk of the spread of the epidemic is relatively small. Among them, nucleic acid screening is crucial, which can quickly identify and lock in the source of infection and reduce the risk of the spread of the epidemic.

It should also be noted that behind this technological upgrade is a scientific and rigorous exploration process. The medical treatment team of the joint prevention and control mechanism of the State Council actively organized professional institutions and expert demonstrations, studied and proposed technical methods to further improve the efficiency of nucleic acid detection, carried out clinical real sample verification, organized and formulated the "New Coronavirus Nucleic Acid 20-in-1 Mixed Sampling And Detection Technical Specifications", and gave specific and detailed operational requirements for multiple links, which is conducive to preventing missed tests and ensuring the quality of nucleic acid testing.

It is worth noting that the 20-in-1 mixed harvest detection is more suitable for large-scale population nucleic acid screening in emergency situations. After all, in non-emergency state or routine nucleic acid testing, once the mixed sampling test result is positive, gray area or positive for a single target, it is necessary to control the risk of 20 people at the first time, and the impact is relatively large. Therefore, when applying this technology specifically, it is necessary to adapt to local conditions and time conditions.

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