In the hepatitis B laboratory, people are most familiar with the detection of three antigens and antibody systems of hepatitis B markers, which is commonly known as the detection of hepatitis B two-and-a-half, including: HBsAg, HBsAb, HBeAg, HBeAb, HBcAb, a total of five viral markers.
What are the implications of these metrics? Here's the answer: (see table below)
(1) Commonly known as the big three yang, indicating that the patient is an HBV carrier or chronic hepatitis, which is contagious.
(2) Acute hepatitis B infection stage or chronic hepatitis B. Less contagious.
(3) Commonly known as xiao sanyang, if the HBV-DNA is lower than the detection level, it means that hepatitis B has tended to stabilize or improve. It is chronic hepatitis B and is weakly contagious.
(4) Previously infected with hepatitis B, but still has immunity.
(5) There is a previous hepatitis B infection, which belongs to the recovery period of acute infection, and a small number of people may be infectious.
(6) There was a hepatitis B infection in the past, or now an acute infection.
(7) Have previously been vaccinated against hepatitis B (antibodies have been produced) or have been previously infected with hepatitis B.
(8) Acute hepatitis B recovery period, previously infected with hepatitis B.
(9) Early acute infection, or chronic hepatitis B surface antigen carriers, weak infectivity.
(10) Chronic hepatitis B surface antigen carriers or acute infection tend to recover.
(11) Early hepatitis B infection, or chronic hepatitis B carriers, is highly contagious.
(12) Acute hepatitis B infection tends to recover, or is a chronic carrier.
Hepatitis B in two halves only reflects HBV infection and replication, and does not fully reflect the severity of the disease. For example, the disease of the big three yangs is not necessarily serious, on the contrary, the small three yangs, the disease is not necessarily mild. To more accurately determine the replication status of the hepatitis B virus and the extent of liver damage, qualitative or quantitative tests of HBV-DNA and ALT should also be done.