Domestic new crown special drugs were approved for listing at the end of the year
China's recovery from COVID-19 is not far off
According to the news of "Finance and Economic Network", according to statistics, there are currently six kinds of new crown special drugs independently developed in China. Among them, BRII-196 and BRII-198, two effective neutralizing antibody drugs jointly developed and screened by Tsinghua University, Shenzhen Third People's Hospital and Tengsheng Huachuang, have participated in the treatment of more than 700 patients in China. The R&D team has submitted conditional listing declaration materials to the State Food and Drug Administration on a rolling basis on October 9, and is expected to obtain approval for conditional listing by the end of December.
Professor Zhang Linqi of Tsinghua University: Hundreds of antibodies isolated from the blood of patients in the convalescent period of the new crown were screened for 2 antibodies with the highest activity and super complementarity, and in clinical trials carried out at home and abroad, they showed an excellent effect of reducing severe illness and mortality by 78%.
At the same time, the neutralizing antibody DXP604, jointly developed by The Xie Xiaoliang team of Peking University and Danxu Biologics, was used as a "sympathetic drug" in Beijing Ditan Hospital when the patient had no other drugs available, and some patients have recovered and been discharged after medication.
According to the relevant person in charge, the current research and development of effective drugs for the new crown virus mainly revolves around blocking the virus from entering the cell, inhibiting virus replication, and regulating the human immune system
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According to the Straits Express, the team led by Professor Huang Ailong of Chongqing Medical University has developed three virus antibodies. It is worth mentioning that the three super-strong antibodies are effectively neutralized in the face of global new coronavirus strains, and even in the face of high infectious and mortality-causing Delta virus strains.
The research team selected three super-strong antibodies from the blood of dozens of new crown patients through monoline cloning to screen more than two hundred antibodies. These three super antibodies can effectively block the new crown virus from entering the human body. In vitro and in vitro experiments, all three antibodies have significant effects on Delta virus! And these three kinds of perturbators are completely different in terms of targeting, even if the new crown virus mutates again, we still have a way to deal with it.
Experts said they will continue to study to find out the types of antibodies to the new crown disease, and once successful, they will create a special anti-epidemic drug belonging to China on a large scale through genetic engineering. A clinical trial phase will take place early next year and will be launched on the market immediately after success. It is believed that soon, China's special drugs to cut off the new crown virus and eradicate the disease will come out, at that time, the people of our country will be able to completely and completely get rid of the new crown epidemic without leaving home.
Based on the above, the author believes that in the fight against the new crown epidemic, China's scientific researchers have always been racing against time. China's new crown drugs finally have a "timetable", and one of the antibody combination drugs is expected to be approved for conditional listing before the end of the year at the earliest. The above is enough to show that China has once again come to the forefront of the world in terms of medical level and prevention and treatment of the new crown virus! It will not only change the situation of local rebound in China's epidemic prevention, but also bring the dawn of eradication of the epidemic to the world. ......
Zhang Xinrong, Hanzhong/Yangxian
2021.11.20.