Clopidogrel and aspirin are both commonly used drugs in patients with cardiovascular disease.
Clopidogrel is a novel antiplatelet drug. Imported about 20 yuan a piece, domestic is cheaper. Although it is expensive, it is also really powerful. Clinically widely used in acute coronary syndrome, myocardial infarction, ischemic stroke and peripheral arterial vascular disease and other fields.
1. Maintain good medication compliance. Take it for a long time as directed by your doctor, and do not stop the drug, increase or decrease the amount. Self-stop or reduce the dose can not achieve the desired therapeutic effect, self-increase has the risk of bleeding, must be paid attention to!
2, clopidogrel before or after meals are ok, try to take regularly, do not eat this morning, eat tomorrow night, so that it is not conducive to the stability of blood concentration, every day basically fixed time period to take, the stability of blood concentration, of course, the treatment effect is also the best.
If missed within 12 hours of the usual time of taking the drug, a standard dose should be taken immediately and the next dose should be taken according to the usual time of administration. After 12 hours of the usual medication time, the standard dose is taken at the next regular medication time, and the dose cannot be increased without supplementation.
3. Taking clopidogrel together with the proton pump inhibitor omeprazole will weaken the efficacy of clopidogrel. Pantoprazole can be used instead of omeprazole if needed.
4. A common adverse reaction caused by clopidogrel is gastrointestinal bleeding. Sometimes it is also necessary to use it with aspirin, pay attention to whether there is bloody stool, black stool or bleeding in other parts of the body, and once found, it is necessary to consult a doctor in time.
5. Clopidogrel must first be metabolized by the liver before it can be converted into an active state to exert anti-thrombotic effect. However, due to genetic differences, some people have poor activity of liver drug enzymes, which will affect the antithrombotic efficacy of clopidogrel. Therefore, if there are many thrombotic events such as myocardial infarction and cerebral infarction after taking clopidogrel, genetic testing of liver drug enzymes is required. #哆咖医生超能团 #