The researchers found that while wild poison dart frogs are highly toxic, captive-bred poison dart frogs are safe and non-toxic. Further research showed that the poison dart frog itself does not synthesize toxins, but rather does so from there

The researchers found that while wild poison dart frogs are highly toxic, captive-bred poison dart frogs are safe and non-toxic. Further research showed that poison dart frogs do not synthesize toxins themselves, but obtain toxins from poisonous foods, such as spiders, ants, ladybugs, horses, etc. After eating these bugs, poison dart frogs store toxins in the poison glands of the skin and release them when necessary. Because of the wide range of recipes, poison dart frogs accumulate various toxins, and more than 800 kinds of poison dart frog toxins have been reported.

Since the poison of the poison dart frog comes from food, why is it not poisoned to death? When the venom of poison dart frogs enters other animals, it binds to specific receptors on nerve cells, interferes with nerve conduction, causes muscle twitches, and stops beating hearts. The poison dart frog has evolved that these receptors mutate and do not bind to toxins, so they are not poisoned.

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