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What does the gap between the two important achievements of Zhang Wenhong's team's new crown research and reality illustrate?

author:Warm and happy
What does the gap between the two important achievements of Zhang Wenhong's team's new crown research and reality illustrate?

Zhang Wenhong is currently the director of the National Medical Center for Infectious Diseases, the leader of the Shanghai New Coronary Pneumonia Medical Treatment Expert Group, and the director of the Shanghai Key Laboratory of Infectious Diseases and Life Safety Emergency Response, and has been at the forefront of new coronavirus research, he and his team have a number of important research results, and won two awards in Shanghai science and technology.

However, after the national epidemic was lifted, careful netizens found that there was a big gap between the research results of Zhang Wenhong's team and reality, what was the main reason? Further exploration is needed.

In September 2022, Zhang Wenhong's team was nominated as the only "special prize" winner in the popular science category of the Shanghai Science and Technology Award. Prior to this, Zhang Wenhong's team published a paper to study and draw conclusions about the new crown pneumonia infection during the lockdown in Shanghai.

The main conclusion is that during the lockdown, there were more than 56,000 local confirmed cases in Shanghai, and more than 550,000 asymptomatic infections. The results of Zhang's team showed that the proportion of all cases in Shanghai was as high as 98%. Even among patients with mild disease, the rate of fever is only 4%.

What does the gap between the two important achievements of Zhang Wenhong's team's new crown research and reality illustrate?

Different from the results of Zhang Wenhong's team, after the full release in early December 2022, in about a month, the infection rate of new crown pneumonia exceeded 80%, and most people had symptoms, many people had high fever, soreness, poor spirits, and some people had a long-term nose without ventilation, cough, and fever even after recovery.

Although there is no specific data support, ordinary people can feel that Shanghai's data is obviously not in line with the facts that happened later, that is, there is no certain reference and comparison value. The results of Zhang Wenhong's team may only be suitable for the situation in Shanghai and the situation in Shanghai at that time.

In other words, this achievement has no reference and guiding significance for the whole country, and has its great limitations.

Recently, Zhang Wenhong visited a number of nursing homes in Shanghai and came to a new conclusion that the proportion of people with symptoms in the latest round of infections in Shanghai is indeed higher than in the first half of the year.

Another research result led by Zhang Wenhong was published in "Emerging Microbes and Infections".

The main content is: the researchers used the basis of two doses of inactivated vaccine to perform the third dose of homologous booster and heterologous booster (sequential vaccination), and found that 14 days after the homologous third booster of inactivated vaccine, the neutralizing antibody titers in serum against the original vaccine strain, Delta strain and Omicron strain increased to 285.6, 250.8 and 48.73, respectively. If the heterologous third dose of recombinant subunit protein seedlings was strengthened for 14 days, the neutralizing antibody titers in serum for the original strain, Delta strain and Omicron strain increased to 1436, 1501 and 95.86, respectively. This study further confirms that the promotion of vaccine booster shots is still one of the effective means to prevent the spread of SARS-CoV-2, especially against the spread of the Omicron strain for suitable people.

The reality is that the vast majority of people on the mainland have generally received a third booster shot, but after this full release, the antibodies in people who have received three booster shots are almost useless in the face of the Omicron virus, as if it has little effect, and the virus has broken through all immune and vaccine protection barriers.

At the same time, it is strange that this time the virus has achieved a precise dimensionality reduction blow on a large scale across the country, the speed of transmission, the strength of transmission, the intensity of transmission, and the wide range of transmission are unexpected, in less than a month, the vast majority of the country has entered the peak of infection, and countless people have been infected.

According to preliminary statistics from Henan, the number of infected people in this wave is more than 80%, and the large-scale infection has caused a short-term medical run, and the rate of severe disease and mortality has also increased significantly, which has had a negative impact on the life safety of the broad masses of the people.

The big contrast between research and reality, many experts are surprised, many people can't understand, what's wrong with this?

What does the gap between the two important achievements of Zhang Wenhong's team's new crown research and reality illustrate?

For Zhang Wenhong and his team, we have no doubt about their professional ability and professionalism, the great contribution they have made to the country and the people during the epidemic, and the authenticity of the epidemic data in Shanghai at that time, because in the face of the epidemic, everyone is carrying the burden and never dares to slack.

However, because the speed of virus mutation exceeds people's imagination, the escape ability of Omicron virus exceeds people's imagination, coupled with the vast territory of our country, large territory, obvious differences in climatic conditions, and the difficulty of epidemic prevention and control is rare in the world. All these have put forward higher requirements and higher standards for our research on the new crown pneumonia epidemic, and at the same time hope that our scientific research staff will face the difficulties, overcome the difficulties as soon as possible, and make the epidemic end as soon as possible.

Therefore, in view of the gap between the research results of Zhang Wenhong's team and reality, can we open up ideas, think and study as a new topic, and then draw more scientific conclusions from it to make new contributions to the comprehensive fight against the new crown pneumonia epidemic.

We should understand that in the face of the new crown pneumonia epidemic, there have never been bystanders!

What does the gap between the two important achievements of Zhang Wenhong's team's new crown research and reality illustrate?

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