Is blood exchange prolongation real? The University of California confirmed: Dilute half of the blood, and the 69-year-old returns to youth
In the age of obscurantism, both the East and the West invariably gave magic to blood: ancient Greek history books vividly recorded the scenes of Greek nobles lying on the wounds of gladiators sucking blood, believing that fresh blood was the antidote to life; Lu Xun's novel "Medicine" records that the owner of the tea house in the old days bought human blood steamed buns from the executioner and used them as medicine for his sick son.
"Ru Mao drinking blood" sounds strange, but it seems that there is a conclusion in the dark, and modern scientists have used technical means to prove that the blood does hide the mystery of youth - blood dilution.
University of California: The key to the rejuvenation of physical indicators lies in blood thinning
The exploration of blood exchange can be traced back to a study published in Nature at Stanford University in 2005, where the Conboy team confirmed through "xenosymbiosis experiments" that exchanging young blood can achieve physiological reversal of organisms.
The researchers selected 40 mice with direct blood relations (to prevent rejection reactions): one group was young mice, one group was old mice, and the combination of old and young was paired one by one, and the blood circulation of the two was connected through surgery to achieve blood exchange.
Dramatically, the old and young mice seem to have an age "swap", the original limbs of the weak old mice, the muscles become strong, the hair is getting darker and brighter day by day, the liver, skin and other physiological indicators turn to younger; On the other hand, the young rats are becoming more and more sluggish, showing a significant decline. It can be seen that blood exchange leads to physiological exchange.
Follow-up studies by scientists followed up on this discovery. After 15 years, Conboy once again confirmed through the "Nature" article that the key to rejuvenation is not the input of young blood, but the dilution of aging blood.
The researchers took the elderly mice as the experimental object, replacing half of the plasma in the elderly mice with a combination of normal salt solution and 5% albumin to achieve dilution of the elderly blood. The experimental results showed that after blood dilution, the muscles of the elderly mice were repaired, the phenomenon of liver fat and fibrosis was reduced, and the hippocampal nerve cells increased by 8 times.
Second, blood thinning: not a foolproof solution
In August this year, Conboy's team conducted human clinical trials to further confirm the rejuvenation potential of blood thinning, and the study was published in the authoritative journal Geroscience. It is worth mentioning that the subject of this experiment is no longer a mouse, but a human.
The experimenters recruited 6 elderly people (average 69 years old) as the experimental group and 2 middle-aged people (average 49 years old) as the control group. Once a month, the elderly group underwent blood thinning (also known as "therapeutic plasmapheresis"), and the results showed that their DNA damage, protein expression and other biomarkers of aging in the human body were reversed, and the number of immune cells increased significantly.
As soon as the results of the experiment were released, they were greatly praised by The Pioneer in the field of "Inhibition" and Harvard Biology Professor Sherkeley. However, it is undeniable that there are still potential risks in "therapeutic plasmapheresis", which may cause complications such as viral infections and allergic reactions, and cannot be extended to all populations.
Third, the biological geeks are crazy continuously, and the hundred-year-old era may come
According to Gawker, peter Thiel, the founder of PayPal and a Silicon Valley billionaire, spends $40,000 a quarter, undergoes blood exchange surgery four times a year, and obtains fresh young blood from the body of an 18-year-old (although this chaos was later severely warned by the US FDA) to enhance energy, and the title of "vampire" was derived.
He boldly promised to "live to 120 years old", and in order to achieve this goal, he insisted on oral hormone drugs every day and participated in the "cryonics program"; American real estate tycoon Ali Rastega, who spends $7,000 (about 47,000 yuan) each time, regularly flies to Mexico to receive stem cell injections.
Behind the bold attempts of biological geeks is the continuous advancement of modern science, although there is still a certain gap from the real promotion of technologies such as blood exchange and cryonics, but the era of everyone's hundred years old may not be so far away#每日养生小常识 #
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